Thymine. Discovered in the late 1940s, this is known as "The Chargaff's Rules": DNA has equal numbers of adenine and thymine residues (A = T) and an equal number of guanine and cytosine (G = C). This was one of the most important features for Watson and Crick to solve the structure of DNA molecule in 1953.
thymine
thymine
thymine
adenine.
adenine
thymine
thymine
thymine
Chargaff's data showed that for each organism he studied the amount of adenine always equaled the amount of thymine (A=T) likewise, the amount of guanine always equaled the amount of cytosine (G=C).
Thymine. Discovered in the late 1940s, this is known as "The Chargaff's Rules": DNA has equal numbers of adenine and thymine residues (A = T) and an equal number of guanine and cytosine (G = C). This was one of the most important features for Watson and Crick to solve the structure of DNA molecule in 1953.
Erwin Chargaff. "In 1949, Erwin Chargaff, a biochemist working at Columbia University, in New York City, made an interesting observation about DNA. Chargaff's data showed that for each organism he studied, the amount of adenine always equaled the amount of thymine (A=T). Likewise, the amount of guanine always equaled the amount of cytosine (C=G). However, the amount of adenine and thymine and of guanine and cytosine varied between different organisms." -From my biology textbook, "Biology: Principles & Explorations," Holt, Rinehart, and Winston.
adenine.
Chargaff made an observation about DNA that was very important in the determination of its structure. He noticed that the amount of adenine always equaled the amount of the thymine, and the amount of cytosine always equaled the amount of guanine. This principle is known as chargaffs rule, and it helped Watson and crick eventually realize that A paired with T and C paired with G.
Adenine always binds with thymine.
In DNA replication, adenine binds with thymine. In RNA, adenine binds with uracil.
adenine with thymine cytosine with guanine adenine with uracil cytosine with guanine
adenine