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NNE is the direction you would fly.
Only certain people are allowed to travel to Cuba, I know of professors, religious and humanitarian organizations. Since Puerto Rico belongs to the U.S. the embargo is enforced here too. Because no airplane flies from San Juan to Cuba, most people who go there usually take a flight to some Central or South American country like Panama and then fly to Cuba from there.
around 6 hours
North West
south
South
the last time people to fly to cuba was in 1987 if my calculations are correct
7000 miles
From Caracas to Brasilia, a bird would have to fly South East
Up would be best, then fly east.
by plane.
north by northwest