It depends on the car.
But generally speaking, yes 426 is quite a bit or horsepower.
426 horsepower (manual transmission) 400 horsepower (automatic transmission) http://www.caranddriver.com/reviews/car/09q1/2010_chevrolet_camaro_ss_v8-short_take_road_test
426
48
Hot Rod magazine added 259hp with a 8-71 to a 426 crate motor- 753hp
400 with automatic, 426 with manual tranny
426 w/6-speed, 400 w/automatic.
Manual (LS3): 426 hp Automatic (L99): 400 hp
426 hp (manual transmission) 400 hp (automatic transmission)
426 hemi
A World of Outlaws sprint car engine can vary from about 810 horsepower to about 900 horsepower.
the horsepower of a car depends on the number of cylinders it has. The engine displacement does not affect the horsepower of a car by much.
The manual-gearbox Camaro SS has 426 horsepower and 420 lb-ft of torque.