An alkylating agent is a compound that's capable to replace a hydrogen for an alkyl group to a specific place on a molecule. Alkylating agents attacks mostly on a nitrogen, oxygen or sulfur. Common alkylating agents are: Methyl iodide(or other haloalkanes), dimethylsulfate and some carboxylic acid alkyl esters.
An alkylating agent is a compound that's capable to replace a hydrogen for an alkyl group to a specific place on a molecule. Alkylating agents attacks mostly on a nitrogen, oxygen or sulfur. Common alkylating agents are: Methyl iodide(or other haloalkanes), dimethylsulfate and some carboxylic acid alkyl esters.
It causes DNA strands in cells to break and rearrange
Alkylating drugs kill cancer cells by directly attacking DNA, the genetic material of the genes. Cyclophosphamide is an alkylating drug.
Chlorambucil is a nitrogen mustard alkylating agent. The drug chlorambucil is used in chemotherapy to treat chronic lymphocyte leukemia (cancer).
immunomodulators alkylating drugs alkylating agents nitrogen mustard
The gas commonly used in gas sterilization is ethylene oxide (EtO).
žNitrogen mustards: such as mechlorethamine (nitrogen mustard), chlorambucil, Cyclophosphamide (Cytoxan), ifosfamide, and melphalanžžNitrosoureas:streptozocin, carmustine (BCNU), and lomustinežAlkyl sulfonates: busulfanžžTriazines: dacarbazine (DTIC) and temozolomide (Temodar)žžEthylenimines: thiotepa and altretamine (hexamethylmelamine)žThe platinum drugs (cisplatin, carboplatin, and oxalaplatin) are sometimes grouped with alkylating agents because they kill cells in a similar way.
Oil refining is the process of distilling oil and then further reforming, catalytic cracking, hydrofining, blending, and sometimes coking, hydrocracking, alkylating various fractions of the distilled oil.
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