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Is colitis hereditary

Updated: 9/15/2023
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15y ago

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Yes and no. The cause of Inflammatory Bowel Diseases are multifactorial, and still under investigation. Crohn's shows a greater familial concordance than ulcerative colitis, and certain genes are of interest that have been shown to exist more frequently within IBD sufferers than non-sufferers, but it is likely an interplay of enviromental factors with these genes of interest that predispose's one to either Crohn's or UC. Environmental triggers of interest are: western lifestyle, excesive hygiene, inadequate vitamin d production, antibiotic use, early life consumption of refrigerated products, accutane...

I have 3 sibling with ulcerative colitis, and now I have been diagnosed with it. Recent research has pinpointed a genetic mutation in some families. Normal people (people without the disease) have a colon that releases a protective coating during times of stress. Those with the mutated gene have colons that do not release the protection. It's still a hypothesis from what I understand, but it sounds pretty logical to me. Each of us were diagnosed with the disease after times of extreme stress in our lives.

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Archibald Bernier

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Q: Is colitis hereditary
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