Asked in Hemophilia
Is haemophilia a result of translocation?
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Asked in Conditions and Diseases
What is Haemophillia?
Haemophilia is a famous disease; it came from the queen Victoria and her offspring, it's a blood disorder. The symptoms range from easy bruising to prolonged bleeding. Bleeding can occur spontaneously or as a result of injury. The disease is sex linked. There is no cure for Haemophilia but patients are treated with frequent medical care.
How do people suffer with haemophilia?
Haemophilia is a genetic disorder. Usually males are the victims and females are carriers of this disease. There is no prominent cause of this disease but now-a-days it is seen that the families which do not have any history of haemophilia may also have a haemophiliac child. The reason for this is that sometimes there is mutation at genetic level which may lead to deficiency of clotting factor(VIII OR IX) in the blood of the child resulting in haemophilia. One may also suffer from haemophilia at a very later stage of his life but that is very rare. This is the case of Acquired Haemophilia.
Does hemophilia skip a generation?
Haemophilia is a sex-linked recessive disorder - which means it can skip a generation, but only if it is carried in the female line. A female can be a carrier of haemophilia, but a male cannot. This is because males only have one X chromosome, so if they have a defective X they will have the disorder. If a father has haemophilia, all of his daughters will also have haemophilia.
Which hemophilia disorder is genetic?
i believe all types of haemophilia are genetic although i am not sure. but i do know that CLASSIC HAEMOPHILIA is a genetic disorder Haemophilia A and B are both genetic. Haemophilia A (which is the most common) occurs when your blood lacks a clotting agent called factor 8. Haemophilia B occurs when you lack factor 9 in your blood. There is also acquired Haemophilia, this occurs when the immune system starts attacking clotting agents within the blood, this usually occurs in elderly people. Both forms of genetic haemophilia mostly occur in males, it rarely occurs in females. Unfortunately there is no cure but it is quite easily controlled with injections of the missing clotting agent.
Is hemophilia a result of translocation?
It can be. Basically most mutations (regardless of type; translocation, reversal, transcription, etc...) can cause hemophilia if they occur within a specific part of the genetic sequencing that codes for the production of the clotting factor proteins. This genetic sequence if found in a segment of the X chromosome.
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