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(I am not a doctor)  I have been taking 300mgs of Lamictal once a day for 10 years due to a seizure disorder and in that time I have been prescribed vicodin for a few dental issues.  I noticed no adverse effects.  It may be only subjective, but I did notice that it wasn't as effective as ibuprofen.  So it is possible that Lamictal may reduce the effectiveness of vicodin.  But as with any drug you are unsure about, always consider what other medications you are currently prescribed.  

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15y ago

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