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How does methotrexate affect lungs?
Lung toxicity can occur within months of methotrexate therapy. It occurs in two to seven percent of patients receiving the drug.
Is Diet Coke contraindicated in methotrexate patients?
There are not true interactions, but diet sodas can add more strain to the kidneys and liver, which are already under stress from the methotrexate.
What are the side effects of methotrexate and entanercept together?
Source: rx2040. com Possible side effect Methotrexate is usually well tolerated but some patients may develop mouth sores, stomach upset, and low white blood counts. Methotrexate is known to be toxic to the liver, kidneys, lung and bone marrow. Blood tests should be done on a regular basis while treatment with this drug. Other adverse reactions may include headache, drowsiness and allergic reactions such as skin rash, itching, dizziness, and hair loss.
Can you take Tylenol and methotrexate?
caution Due to aspirin's effect on platelet aggregation and GI mucosa, aspirin should be used cautiously in patients with thrombocytopenia following treatment with antineoplastic agents due to an increased risk of bleeding.[5717] In general, because certain antineoplastic agents can cause clinically significant thrombocytopenia, they may increase the risk of aspirin-associated bleeding (i.e. GI bleeding, inhibited platelet aggregation, and prolonged bleeding time). Also, aspirin may mask signs of infection such as fever and pain in patients following treatment with antineoplastic agents or immunosuppressives.[6859] Aspirin, ASA should be used with caution in patients receiving immunosuppressive therapy. Although usually seen with large salicylate doses, aspirin may displace mercaptopurine, 6-MP from secondary binding sites, resulting in bone marrow toxicities and blood dyscrasias.[5232] Special consideration should be given to myelosuppressed patients prior to receiving aspirin. Due to the thrombocytopenic effects of methotrexate,[5067] when used as an antineoplastic agent, an additive risk of bleeding may be seen in patients receiving concomitant anticoagulants, platelet inhibitors (also see salicylates), strontium-89 chloride, or thrombolytic agents. Caution should be exercised when salicylates are given in combination with methotrexate. Since both are weak acids, salicylates can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any of these drugs be used cautiously with methotrexate even when methotrexate is used in low doses for the treatment of rheumatoid arthritis. A significantly higher incidence of leukopenia has been reported in patients taking aspirin during methotrexate therapy. Bismuth subsalicylate may have similar effects. In addition, large doses of salicylates (>= 3-4 g/day) can cause hypoprothrombinemia,[5170] an additional risk factor for bleeding. Caution should be exercised when aspirin is given in combination with methotrexate. Concomitant administration of salicylates with high-dose methotrexate therapy has been reported to elevate and prolong serum concentrations of methotrexate resulting in deaths from severe hematologic and gastrointestinal toxicity. Although the risk for drug interactions with methotrexate is greatest during high-dose methotrexate therapy, it has been recommended that any salicylate be used cautiously with methotrexate even when lower doses of methotrexate are given for the treatment of rheumatoid arthritis or psoriasis. Elderly patients and patients with renal impairment may be at particular risk. As both methotrexate and salicylates are weak acids, aspirin can impair the renal secretion of methotrexate and increase the risk of methotrexate toxicity. Salicylates can also displace methotrexate from protein-binding sites.[5067] [5232]
Is simponi effective without methotrexate?
In the U.S., Simponi is approved as a 50 mg subcutaneous injection once a month and is indicatedIn combination with methotrexate for the treatment of adult patients with moderately to severely active rheumatoid arthritisAlone or in combination with methotrexate for the treatment of adult patients with active psoriatic arthritisFor the treatment of adult patients with active ankylosing spondylitisSimponi is available in two dosage forms. The Simponi SmartJect is a novel autoinjector designed to meet the needs of arthritis patients that has received the Ease-of-Use Commendation by the Arthritis Foundation. Simponi is also available as an easy to use prefilled syringe.
What color for methotrexate?
Methotrexate is usually yellow.
What are the sideffects of N-acetylcsyteine on patient taking methotrexate?
The anti-inflammatory actions of methotrexate are critically dependent upon the production of ROS; thus, although NAC therapy has been suggested for rheumatoid arthritis, it should not be prescribed to patients taking methotrexate This material is sourced from the following article( N-acetylcysteine - passe-partout or much ado about nothing?) and can be seen by following the related link below.
Is methotrexate gluten free?
Yes, methotrexate is gluten free.
What is the Size needle for methotrexate?
Methotrexate uses insulin needles.
Is there an over the counter substitute for methotrexate?
Rheumatrex (Methotrexate) or Generic Methotrexate Source: rx2040. com 2,5mg - $0.77 per pill
How Can Annual Check - Ups Be Benifical?
it keeps you update about your health
When did the delegates sign the Constitution?
Because it was benifical to their pooping systems
