it is carried by both males and females
but technically the cause of it is when chromosome 15 from the father is not passed on. so they child only gets the chromosome from the mother. so is it from the mother or father? it cant be both can it? the father's chromosome dissapears, so the mothers replaces it. it is so confusing.
Remember that each parent contributes 1 allele, or copy of a chromosome. So in Prader Willi, the mother's allele is imprinted, or silenced and so you're depending on the father's allele for expression. But unfortunately, in PW you get deletion of the father's allele, which is why disease occurs. So yes- can occur in both males and females bc we're not talking about sex chromosomes here.
Both boys and girls can be affected by this particular medical condition.
Andrea Prader, Heinrich Willi, Alexis Labhart, Andrew Ziegler and Guido Franconi were first to observe Prader Willi Syndrome in 1956.
no
no
Prader-Willi Syndrome is a non-inherited genetic mutation/error that occurs at conception. It impacts males and females (pretty equally) and occurs across all races/ethnicities. See related link
A person inherits Prader-Willi syndrome from the paternal chromosomes. This basically means that you had seven genes that were unexpressed.
Yes he does.
There are no guidelines for preventing Prader-Willi syndrome. Prader-Willi Syndrome is a result of a genetic "error" that occurs at conception therefore there is nothing that can be done to prevent it. Liken it to not being able to prevent hair color or eye color....two things that occur as a result of DNA at conception.
1 in 15,000 people have it
Prader-Willi Syndrome
According to the research I've done, Prader-Willi Syndrome is rarely a result of translocation, but it is a possibility. Translocation in this syndrome results in an inactivation of genes on the paternal chromosome 15.
Chromosome 15q partial deletion is the name for this syndrome.
It was named after the two doctors who diagnosed it