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Q: Is the concentration of cyclin constant throughout the cell cycle?
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Describe the relative concentrations of MPF and its constituent molecules throughout the cell cycle?

MPF - complex of cyclin and cdk that initiates mitosis by phosphorylating protein and other kinases; highest concentration at metaphase Cdk - levels are constant throughout the cell cycle Cyclin - levels vary because it is broken down by MPF after anaphase


What questions might scientists have asked following the discovery of cyclin?

What is the function of a cyclin?How is cyclin expression regulates?Why do protein levels of the cyclins fluctuate throughout the cell cycle?


What molecules control the cell cycle?

Cyclin dependent kinase


Describe the roles of checkpoint cyclin CDK and MPF in the cell-cycle control system?

Cyclin is a regulatory protein that a kinase much be attached to. Cyclin gets its name from its cyclically fluctuating concentraion in the cell. Because of this requirement, these kinases are called cyclin-dependent kinases, CDK's. The CDK rises and falls with changes in the concentration of its cyclic partner. The first cyclin-CDK complex discovered was the MPF. The peaks of MPF activity correspond to the peaks of cyclin concentration. MPF stands for maturation-promoting factors. Basically, the rhythmic fluctuations in the abundance and activity of cell cycle control molecules pace the sequential events of the cell cycle. These regulatory molecules are proteins; kinase, and other enzymes. Particular protein kinases give the "go-ahead" signals at the G1 and G2 checkpoints.


What substances form the cyclin-cyclin dependent kinase combinations that control the stages in the cycle?

proteins and enzyme


What causes the MPF complex to initiate mitosis in the cell cycle?

The decline of Mitosis-promoting factor (MPF) is due to the decline of cyclin.


What is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?

A) MPF B) Cdk C) PDGF D) Protein kinase E) cyclin the answer is E, cyclin. AP Bio student.


Function of cyclin in the cell cycle?

The role is cyclins is to bind with Cdks to propel the cell through the next stage of the cell cycle as they are regulatory subunits. The cyclin part of the complex formed after binding with the cyclin-dependent protein kinase. Cyclin levels are very high especially when the cell is ready to progress to the next stage of the cell cycle, and after the cell is in the next stage, the cyclins are degraded until they are needed by the cell again.


What are cyclin?

They are a group of proteins involved in cell cycle regulation. (Mostly Timing)


What is the category of enzymes that control the cell cycle called?

Cyclin-dependent kinases.


What is the family of molecules that control the cell cycle?

cyclin dependent kinases,CDK's


What are cell cycle regulators are?

These are cyclin dependent kinases (CDKs).