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No. Sexual reproduction process does not depend upon the number of chromosomes in an organism. Chromosome numbers usually are expressed in sets. 2 sets of chromosomes are present in body cells of organisms. For example, human bears 23 pairs which means 46 numbers of chromosomes. The cells with 2 sets of chromosomes are called diploid cells (2n) and haploid cells contain only one set (n) of chromosomes. Gamete cells are always haploid which are obtained by meiosis cell division of diploid cells. In sexual reproduction fusion of two haploid gametes (male and female) results in formation of zygote which id diploid.So, the number of chromosomes present ina cell whether it is small (cat - 38 chromosomes) or large (butterfly- 380 chromosomes) does not affect sexual reproduction.

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Q: Is the presence of large number of chromosomes in an organism a hindrance to sexual reproduction?
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