Conditions and Diseases
The Difference Between
English to Korean

Is there a cure for CIPA if so what is it adn what causes CIPA?

User Avatar
Wiki User
June 08, 2007 8:13AM

Definition: Congenital insensitivity to pain with anhidrosis (CIPA) is a rare inherited disorder of the nervous system which prevents the sensation of pain, heat, and cold. A person with CIPA cannot feel pain or differentiate extreme temperatures. "Anhidrosis" means the body does not sweat, and "congenital" means that the condition is present from birth.

Symptoms: Patients with this disorder are very likely to injure themselves in ways that would normally be prevented by feeling pain. The main features of the disorder are: lack of pain sensation, painless injuries of the arms, legs and oral structures, fever during hot weather because of inability to sweat, mental retardation, infection and scarring of the tongue, lips and gums, chronic infections of bones and joints, bone fractures, multiple scars, osteomyelitis and joint deformities, which may lead to amputation. People with this disorder may not be able to feel a physical orgasm.

Cause: CIPA is caused by a genetic mutation which prevents the formation of nerve cells which are responsible for transmitting signals of pain, heat, and cold to the brain. Overheating kills more than half of all children with CIPA before age 3.

Cure: there is no cure for CIPA at the moment but therapy is avalable