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Yes they use a different chamber size which may cause failure.

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Q: Is there any issues with using a 22 long rifle cartrige in a handgun designed to use 22 magnum?
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What cartrige is larger 7mm Remington magnum or the 30-06 Remington rifle cartrige?

The 7mm Remingtonn is longer. The 30/06 has a larger projectile.


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