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An LC50 test determines the lethal concentration of a substance that causes death in 50% of a test population, typically aquatic organisms such as fish or invertebrates. By exposing these organisms to varying concentrations of water samples, researchers can assess the toxicity of the water. If the LC50 value is low, it indicates high toxicity and potential pollution, while a higher LC50 suggests lower toxicity and better water quality. Thus, the test helps evaluate the impact of pollutants on aquatic life and overall water health.
Toxicity is typically measured in terms of lethal dose (LD50), which represents the dose at which 50% of the test subjects exposed to a substance die. Other measures of toxicity include LC50 (lethal concentration) for gases and EC50 (effective concentration) for substances that don't necessarily cause death but have a measurable effect on an organism.
LD50 or LC50 refers to the dose of a substance that is lethal to 50% of the test population. For phosphoric acid, the LD50 (oral, rat) is estimated to be around 1530 mg/kg. LC50 (inhalation, rat) is not readily available. As with any substance, caution should be taken when handling phosphoric acid due to its potential toxicity.
Hazard Class 6 contains poisonous materials (6.1) and infectious agents (6.2). Division 6.1: Poisonous material is a material, other than a gas, which is known to be so toxic to humans as to afford a hazard to health during transportation, or which, in the absence of adequate data on human toxicity:Is presumed to be toxic to humans because it falls within any one of the following categories when tested on laboratory animals (whenever possible, animal test data that has been reported in the chemical literature should be used):Oral Toxicity: A liquid with an LD50 for acute oral toxicity of not more than 500 mg/kg or a solid with an LD50 for acute oral toxicity of not more than 200 mg/kg.Dermal Toxicity. A material with an LD50 for acute dermal toxicity of not more than 1000 mg/kg.Inhalation Toxicity: A dust or mist with an LC50 for acute toxicity on inhalation of not more than 10 mg/L; or a material with a saturated vapor concentration in air at 20 °C (68 °F) of more than one-fifth of the LC50 for acute toxicity on inhalation of vapors and with an LC50 for acute toxicity on inhalation of vapors of not more than 5000 ml/m³; or
Lead is a cumulative poison, meaning it builds up in your system. The more often you have contact with it, the more precautions you should take. If you handle it often, it's important that you obtain and use good protection. As always, when in doubt, exercise increased caution. My greatest concern is human well being!
LD50 (lethal dose for 50% of a population) and LC50 (lethal concentration for 50% of a population) are designed through controlled experiments that assess the toxicity of a substance. Researchers typically expose a group of test organisms to varying doses or concentrations of the substance to determine the level at which 50% of the subjects experience lethal effects. The data is then analyzed statistically to calculate the median lethal dose or concentration, providing a measure of the substance's acute toxicity. This information is critical for risk assessment and regulatory purposes.
The relationship between the degree of response of the organisms and the quantity of the chemical always assumes a classic concentration-response form. The graphs represent the results of tests in which groups of the organisms of the same species were exposed to various concentrations of a chemical for a specific length of time. The least variability in the curve is at the 50% level of response. The concentration at which 50% level of the individuals react after a specified length of exposure is used as a measure of the activity or toxicity of the chemical agent. In determining the relative toxicity of a new chemical to aquatic organisms, an acute toxicity test is first conducted to estimate the median lethal concentration of the chemical in the water to which test organisms are exposed. LC50 is the concentration estimated to produce mortality in 50% of a test population over a specific time period.
15 years old
you can use analyze <regression <probit
Poison is typically measured in terms of its toxicity, which is often described using units such as LD50 (lethal dose for 50% of the population) or LC50 (lethal concentration for 50% of a population). These measurements help determine the lethal dosage or concentration of a substance that can cause harm or death to living organisms.
According to the manufacturer's MSDS it is only an irritant, not toxic and has no known value for either LD50 (a standard measure of toxicity) or LC50 (a standard measure of carcinogenicity). Its biggest hazards are that it bonds both skin and mucus membranes instantly and that it can decompose at high temperature.For specific details consult the MSDS at:http://www.krazyglue.com/docs/default-source/MSDS-Sheets/mkg0925.htm?sfvrsn=0For what its worth, cyanoacrylate adhesives similar to KrazyGlue are now being used in some types of surgery instead of sutures and after several weeks during healing the body breaks down and absorbs the adhesive with no harm at all.
To obtain LC50 and LC90 values using probit analysis in SPSS, first, organize your data with the dose levels and the corresponding binary response (e.g., dead/alive) for each treatment group. Next, navigate to "Analyze" > "Regression" > "Probit" in SPSS, and input your variables accordingly. After running the analysis, check the output for the probit model coefficients, which can be used to calculate the LC50 and LC90 values by determining the doses corresponding to the 50% and 90% mortality probabilities, respectively. You can also use the "Probit" or "Logit" option under "Analyze" to directly estimate these lethal concentrations based on your data.