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I wouldn't risk it. The colour and smell change would be enough to convince me not to. Although, once that happened to me. It was minced meat instead, part was brown and it had a wrenk odour, I simply took out the brown part and cooked it in lots of seasoning, and it tasted good. However, the smell could be due to the length of period it has been in the freezer for, mingling with other foods, and the brown could be the settling of the hamburger fluids on one side of it. Just cook it really good, not rare please.

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13y ago
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Q: Is your hamburger meat bad if half of its brown after defrosting in microwave...It also smelled different?
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