Did you use factory plugs (NGK)? The aftermarket brands (splitfire, various other multi-tip platinums) do not work as well as the OEM AC/Delco plugs, which are actually made by NGK. It sounds good, but for some reason do not perform well. Check the coil packs and shunts to make sure they are in good condition and properly fitted and tight. Make sure you torque the plugs down using a torque wrench to 20ft-lbs. When I changed my plugs at 90K miles, I missed something, and the car sputtered until I took the plugs back out and rechecked and reset everything. After that, it ran like a champ. Other stupid stuff like clogged fuel filter, plugged up PCV valve, leaky vacuum hoses, etc, can cause the engine to run rough suddenly. Make sure you didn't mess up something like this in the process of re-plugging.
I removed the following: Try resetting the engine controller by disconnecting the battery for 5 minutes and reconnecting. After that, the car may run a bit rough until all the sensor settings readjust to the new exhaust composition. Because that doesn't work on GM cars after 1996. Make sure all of the connections are tight.
what year and what engine??
called a miss, means either no spark, no compression, no fuel, or no air. probably fuel or spark. how old are the spark plugs and cables, they need to be replaced every so often. that is the most common cause. sometimes it can be worse.
What is wrong with it?
you have a short where negative is touching the metal of the car or it is grounded inproperly
wrong plugs or wrong gap!
Vacuum leak?
Replace the ignition control module
either wrong spark plugs or sparkplug gap or you have to plug wires on wrong plugs
CHECK THE IGNITION SWITCH,,, THEY HAVE A HABIT OF GOING BAD
First guess would be that you crossed a couple of plug wires and got the firing order off. Check to make sure you got the plug wires connected to the correct plugs.
check your battery or you spark plugs
Were the spark plugs oil fouled? If so it can be a valve cover gasket, oil would be leaking into your spark plugs.