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Diabetic neuropathy is probably an effect of sustained oxidation (burning) of sensitive capillaries and nerves where they're smallest: in the extremities. The oxidation comes from hyperglycemia, high blood sugar, which is the primary symptom of poorly-treated Diabetes.
Glucose in small amounts in the blood is absolutely required to sustain life: It provides the fuel for most body functions. But in a diabetic, this glucose is not allowed into the body cells and much of it remains in the blood, until the blood glucose levels themselves become dangerous. Glucose in high concentrations is an oxidizing agent, meaning it grabs spare electrons from nearby molecules. Since oxidization is basically the same as burning, the effect of this "glucose toxicity" is similar to slowly scorching the nearby tissues with a slow-burning flame.
Over time, more and more of the small capillaries and nerves in the extremities become damaged, leading to tingling, numbness, loss of circulation, paralysis, and eventually tissue death. Fingers and toes can necrotize (die), and need to be amputated.
Damage from high blood sugar can easily accumulate faster than you can heal it. The way to prevent all this, if diabetic, is to keep your blood sugar within or near normal ranges at all times.
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am i considered a diabetic if my long term reading is 7.2?
am i considered a diabetic if my long term reading is 7.2
The affects of short term and long term?
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Which aspect of the nervous system is involved with diabetes?
The brain, spinal column, and the nerves. Diabetic neuropathy is long-term damage to the nerve fibres. It happens when high blood glucose levels are present over several years. In diabetes, the form it usually first takes is reduced sensation in the feet.
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Endocrinology - Diabetic Neuropathy?
Diabetic neuropathy is a complication of type 1 diabetes. It is most commonly among type 1 diabetics with poorly controlled blood glucose levels, but can also develop in long term diabetics with well-controlled blood glucose levels. The exact etiology of diabetic neuropathy remains unknown, but research suggests that damage to the vasa nervorum, tiny blood vessels that supply the nerves, plays a pivotal role.Diabetic neuropathy expresses symptoms that differ depending upon the group of nerves affected. The most common type of diabetic neuropathy affects peripheral nerves and causes numbness or tingling in the hands or feet. The pain or loss of feeling can extend into the arms and legs. The tingling sensation ranges from a mild prickling to the feeling that person has stepped on a tack or needle. Although these sensations are uncomfortable and can be debilitating, the complete loss of sensation is more problematic. Without feeling in the extremities, patients can suffer burns of cuts and not recognize the danger until significant damage has been done.When the neuropathy damages the autonomic nerves, the heart, lungs, digestive system and sexual organs are affected. Symptoms of autonomic neuropathy include blood pressure issues, changes in bowel or bladder control, lack of sexual response, or digestive issues. In severe cases the stomach fails to recognize the presence of food and fails to secrete digestive enzymes.A third type of diabetic neuropathy affects a single nerve or nerve group. Known as focal neuropathy, it can affect any nerve in the body. Third nerve palsy is a common example. In third nerve palsy, a single nerve controlling a particular movement of the eye is affected. The result is a loss of ability to move the eye in a certain direction. This condition typically lasts for only one to six months and corrects itself.Careful control of blood sugar levels is the only way to avoid diabetic neuropathy, and it may develop over time even with careful control. Although diagnoses are made based on symptoms, nerve conduction studies can document the progression or stasis of damage. Treatment is limited to pain control and prevention of additional nerve damage by better blood glucose control.Tricyclic or other antidepressants are FDA-approved for the treatment of diabetic neuropathy, as are certain anticonvulsants and opioids. These treatments require a prescription. OTC treatment with capsaicin cream is beneficial for some patients, and several studies have shown that alpha-lipoic acid and evening primrose oil supplements can be effective treatments. Researchers are currently investigating electric nerve stimulation as a treatment option.
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