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Q: Long term effects of not having a spleen?
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Having reoccurring Bronchitis, emphysema, and lung cancer


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Leukemia is a cancer made of white blood cells; it can be found in the blood stream, but may also set up shop in the bone marrow and the lymphatic organs such as lymph nodes and the spleen. The short term effects are typically related to acute immune system dysfunction - fatigue, exercise intolerance, a feeling that "you are always sick with something"; some patients also find they bruise easily. Long term effects are typically related to space-occupying lesions - enlarged lymph nodes, an enlarged spleen, susceptibility to minor and rare illnesses such as fungal infection, anemia and bruising. Leukemia, if not treated, is eventually fatal.