Mast cells lead to allergic response which might be harmful to human body then why are mast cells present in your body and how are they useful to the body?

Answer 1

Mast cells are helpful to the physical body because they help iniate an inflammatory response. Inflammation is used by the physical body to defend it'self against incoming antigens that could potentially harm the body. Inflammation is an immune system adaptation and most sources refer to it as a secondary form of non-specific immunity. The reason Mast Cells are usefull is because they are the cells that have cell identity markers on them. Mast cells are a type of wbc that differentiates into a mast cell when it leaves the cardio-vascular system and moves into the tissue. Mast cells are able to recognise a potentially harmful substance. The value of this is that mast cells are able to produce and allergic reaction and this attracts macrophages and other WBC's which ensure that the potentially harmful substance is isolated and distroyed. The body sees the positive aspect of removing the potentially harmful substance as more important than the negatives associated with inflammation.