The driving distance between Chicago, IL and St. Louis, MO is approximately 300 miles. The driving time would be approximately 5 hours 15 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)
It is 410.9 Miles and about a 6 and a half hour drive
It is 300 miles according to Google Maps.
Chicago is 345 miles (555 kilometers) from Missouri.
According to Mapquest.com it takes 4 hours and 48 minutes to drive the 297 miles from Chicago Illinois to St. Louis Missouri
According to Mapquest.com it takes 4 hours and 48 minutes to drive the 297 miles from Chicago Illinois to St. Louis Missouri
Evansville, Indiana is 309 miles south of Chicago. St. Louiis, Missouri is 300 miles southwest of Chicago.
It is 380 miles according to Google Maps.
300 miles,
It is 385 miles according to Google Maps.
790 miles
It is about 298 miles.
925 miles down I-57 and I-55 (they meet in Missouri) SOUTH.