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Can Cause Serotonin disease. I am on zoloft and take vyvanse every once in a while. The two together increase the symptons felt when taking a vyvanse. Its pretty sweet

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Q: Mixing Vyvanse and Zoloft
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What is the best schedule for Vyvanse zoloft and xanax for optimal absorption and therapeutic benefits?

Becareful with this combo, be aware of the risk of serotonin syndrome which is rare but serious so just be conscious of what the symptoms are just in case. I would say from my experience the best schedule for these drugs would be Zoloft first thing in the AM before you even get out of bed then have high protein breakfast because protein helps amphetamine cross the blood brain barrier then take your vyvanse, if you have coffee in the morning make sure you drink it before the vyvanse kicks in otherwise you could have a major anxiety attack then save the Xanax for as soon as you feel the comedown from vyvanse. If you take Xanax before or while vyvanse is peaking you'll kill both the vyvanse and it's pointless. Zoloft like any anti depressant should be taken around the same time eberydayn This is what has worked for but again be very self aware of what your playing with and be honest with yourself with dosage. My best advice from being on this combo for a while is lay off the Xanax and only use it for emergencies (IE panic attacks) if you use it for general daily anxiety or to sleep its very easy to become dependent and that's a slippery slope to addiction. Do some research on what makes vyvanse (dextroampetimine) more effective and add those things do your daily routine like staying away from acidic drinks during the day (a glass of OJ will almost completely nullify my vyvanse) start taking in lots of protein like protein shakes and drink tons of water


Can mixing Adderall and Vyvanse be harmful?

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Does Vyvanse contain aspirin?

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