Mr and Mrs = Familie
Frau und Mann is the translation in German. It is translated from English to German. German is mostly spoken in the European countries.
frau
Willkommen Herr and Frau Welkenbach.
Mr and Mrs
"Frau", the German word equivalent of "Mrs." in English. Because "Herr" is Mr., his spouse would be Mrs.: Frau.
Mr and Mrs is correct or Mrs and Mr is correct
Mr. and Mrs. (ex. "Hello, Mr. and Mrs. Evans" instead of "Hello, Mrs. and Mr. Evans")
Mr. & Mrs. Smith
On an envelope as part of the address: Familie When referring to a couple: die ..... e.g. that's Mr and Mrs Bauer - das sind die Bauers das Ehepaar e.g. that's Mr and Mrs Bauer - das ist das Ehepaar Bauer
In the US it is normally Mr. and Mrs.
Dr. and Mrs. or Mr. and Dr.