A change in pH can alter the ionization of the R groups of the amino acids. When the charges on the amino acids change, hydrogen bonding within the protein molecule changes and the molecule changes shape. The new shape therefore may not be effective
too high or too low pH denatures the enzymes. you will get a small reaction with a base or acid. neutral pH level maximizes reactions
at a ph of 13
The stomach secretes protease enzymes that work best at a pH of around 2.
Following are the factors affectingenzymes:SalinityTemperatureInhibitorsAllosteric factorspH levelSubstate concentrationCatalystEnzyme concentration
temperture.
Temperature, pH, substrate concentration
All enxymes work at an optimum pH. Changes in pH levels could change the rate at which the enzymes work by denaturing them.
enzymes require specific temperature and pH in order to work properly. Otherwise, the temperature or pH change their conformation or disable their ability to bind the substrate because the required electrostatic interactions might not happen under different pH.
Most enzymes only work in a certain pH range; pH is not dependent on the presence of enzymes, however.
too high or too low pH denatures the enzymes. you will get a small reaction with a base or acid. neutral pH level maximizes reactions
tempeture,ph, solute concentration and salt content
Substrate concentration will affect enzymes because substrates are specific to enzymes. The pH will affect enzymes because certain enzymes will work better in certain pH levels.
Enzymes are very pH-sensitive. Any change in pH results in denaturing of proteins.
it can change the shape of enzymes & active site so the enzyme is unable to work
Most enzymes work best at a certain pH, however there are some enzymes that can operate over a broad pH range.
The activity of the enzymes depends on the specific pH needed.
at a ph of 13