They don't react, but caffeine will make salicylic acid work better. If you were to add some acetaminophen to it--three parts acetaminophen, three parts salicylic acid, one part caffeine--you would make the drug called Excedrin, which works really well.
I had a reaction to salicylic acid where it burnt my skin, i suggest moisturizing cream and cortaid cream to soothe your skin and heal it.
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Aspirin is formed in a reaction between salicylic acid and acetic anhydride. In this reaction it is the phenolic alcohol group that reacts to form the aspirin.
Salicylic acid is considered to be a phenolic (aromatic) acid. The -OH group in salicylic acid gives a few tests of alcohols also like esterification, reaction with Na, etc.
Aspirin is made when salicylic acid and acetic anhydride is reacted in the presence of an acid catalyst such as H2SO4. Acetylsalicylic acid (aspirin) and acetic acid is formed. The reaction is an esterification reaction.
Aspirin is a protected name belonging to Bayer A.G. (in some countries) for acetylsalicylic acid. Salicylic acid is a beta-hydroxy acid, meaning that it's both an acid and an alcohol. It serves as the alcohol in the esterification reaction.
37.16% is the expected yield in the reaction of salicylic acid and acetic anhydride used to form aspirin.
The chemical reaction is: One mole of aspirin plus one mole of water yields one mole of salicylic acid plus one mole of acetic acid. Aspirin=C9H8O4 Salicylic acid=C7H6O3 Acetic acid=C4H6O3
2,4,6-tribromophenol is formed by the loss of CO2 (decarbonylation).
Since salicylic acid is being reacted with excess acetic anhydride, salicylic acid is the limiting reactant of the reaction. The balanced equation of the reaction of salicylic acid and acetic anhydride indicates that their is a 1:1:1:1 ratio between every reactant and product. Based on this, it can be concluded that the moles of salicylic acid, if reacted entirely, will yield an equivalent amount of moles of aspirin. To find the theoretical yield, you must know the molecular weight of aspirin and salicylic acid. First, the amount of moles of salicylic acid must be calculated by dividing the gram amount of salicylic acid, which is 85 grams, and dividing it by its molecular weight, which is 138.12 grams per mole.85.0/138.12= 0.615 moles of salicylic acidThis is the mole amount of salicylic acid as well as the theoretical mole amount of aspirin. To convert the mole amount of aspirin into grams, this figure be multiplied by the molecular weight of aspirin, which is 180.15980.615 x 180.1598 = 111 grams of aspirin (when rounded to 3 significant figures)
Because Salicylic Acid reacts with Acetic Anhydride in the presence of H2SO4 and CH3COOH to give Aspirin. The sulphuric acid does not react. If you measure the volume/weight of the acid before the reaction and after the reaction, there will be no change. Note:-You can also use Acetyl Chloride in the presence of phosphoric acid instead on Acetic Anhydride.
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