Romazicon/Roche (Flumazenil) is a specific benzodiazepine receptor antagonist indicated for the reversal of the CNS depressant effects of the benzodiazepines. It is contraindicated where multiple agents (ie: tricyclic antidepressants) have also been used concomitantly. Given that Flumazenil is a benzodiazepine receptor antagonist, it must be borne in mind that seizures may be invoked in individuals whom are physically dependent on benzodiazepines, and hence, it should not be used in this scenario unless absolutely warranted.
flumazenil (Romazicon)
Flumazenil
Flumazenil is sometimes used in the event of accidental benzodiazepine overdose.
Flumazenil (brand name Romazicon US, Anexate CA) is a benzodiazepine receptor antagonist that can be administered in the event of benzodiazepine overdose to stop or reverse their sedative effects.
From Wikipedia: Flumazenil is a benzodiazepine antagonist drug that can be used to treat an overdose of midazolam(dormicum) as well as to reverse sedation.[5] However, flumazenil can trigger seizures in mixed overdoses and in benzodiazepine dependent individuals so is not used in most cases.[7][8]
Flumazenil is a benzodiazepine antagonist that is infrequently used to reverse oversedation during procedural sedation when benzodiazepines are used. It should not be used in overdose situations, as it will cause seizures.
Flumazenil is a benzodiazepine antagonist given *as part of* a treatment for Ativan (and other benzodiazepines) overdose in *hospitalized* patients. Flumazenil itself has its own risks and these risks should be considered by the prescriber.
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"Antidote" is a noun.
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