Shortest route from Columbia MO to Myrtle Beach SC?

Answer 1

1. Take I-70 EAST to I-270 NORTH to CHICAGO at EXIT 232B.
2. Take I-270 to I-255/IL-255 to MEMPHIS and WOOD RIVER at EXIT 7 in Illinois.
3. Follow signs to I-255 SOUTH to MEMPHIS. Take I-255 SOUTH to I-64 to St. Louis and LOUISVILLE at EXIT 20. You want I-64 EAST to LOUISVILLE.
4. Take I-64 EAST through Illinois and Kentucky to I-77 SOUTH in Virginia.
5. Continue on I-75 SOUTH through West Virginia and Virginia to I-74 EAST to MOUNT AIRY and WINSTON-SALEM at EXIT 101 in North Carolina.
6. Take I-74 EAST to US-52 SOUTH. Continue straight on US-52 SOUTH.
7. Stay on US-52 SOUTH to I-40 EAST to GREENSBORO and HIGH POINT at EXIT 107A.
8. Take I-40 EAST to I-73 SOUTH.
9. Continue on I-73 SOUTH to where I-73 (temporarily) ENDS at US-220 just south of Ellerbie.
10. Continue on US-220 SOUTH to US-1 SOUTH. Continue straight on US-1 SOUTH.
11. Take US-1 SOUTH to I-74 EAST.
12. Take I-74 EAST to NC-38 to HAMLET and BENNETSVILLE.
13. Turn right off the exit ramp onto NC-38 SOUTH to BENNETTSVILLE.
14. Take NC-38 SOUTH into South Carolina where it continues as SC-38 SOUTH.
15. Take SC-38 SOUTH to US-501 SOUTH. Continue straight on US-501 SOUTH.
16. Take US-501 SOUTH to Myrtle Beach.