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EASY, one tiny little change in the sequence of a strand of nucleotides making up the DNA could turn normal functioning cells to the sickle cell disease. It is very important that the processes during transcription and translation go smoothly, or something bad could go wrong when a baby is born or something like that. It doesn't take a lot to mess up.

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โˆ™ 10y ago
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โˆ™ 9y ago

Even a single base change in the DNA can lead to radical changes in the protein product. This can occur by the loss of a base pair, addition f a base pair or substitution of a base pair, each potentially stopping the synthesis, or creating a frame-shift change.

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โˆ™ 14y ago

nucleotide sequence itself determines the folding of the protein .correct folding is essential for the protein to be functional. a change in single nucleotide alters the reading frame thus effecting the folding, and function of it.

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โˆ™ 12y ago

A nitrogenous (nitrogen-containing) base is an organic compound that owes

its property as a base to the lone pair of electrons of a nitrogen atom.

-says ChaCha.com

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โˆ™ 13y ago

Im working on that worksheet too... one tiny little change in the sequence of a strand of nucleotides making up the DNA could turn normal functioning cells to the sickle cell disease.

not my words, all credit goes to the other guy! *dont sue.*

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โˆ™ 11y ago

It could change the amino acid sequence of a protein. This could be harmless, or it could produce a change that is lethal.

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Q: How does a change in a nitrogen base alter the formation of a resulting protein?
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