True, if you consider "North America" as the North American subcontinent which includes Canada, the United States, Mexico and Central America.
The Royal and Pontifical University of Mexico (Spanish: Real y Pontifica Universidad de Mexico) was the first university officially founded in North America, on September 21, 1551.It is also the second in the Americas, following the National University of San Marcos in Lima, Peru, founded on May 12 of 1551.
In 1551 a decree by Carlos I established the "Royal and Pontifical University of Mexico" known today as the University of Mexico or la Universidad Nacional Autonimo de México (UNAM). Source: "The Oldest University in America" by C. E. Castañedain
The Universidad Nacional Autonoma de Mexico, or UNAM, was founded on September 22, 1910.
The Royal and Pontifical University of Mexico (in Spanish, the Real y Pontificia Universidad de México) was founded in 1551 by Royal Decree of Charles I of Spain, and is considered the first university officially founded in North America.
In 1551 a decree by Carlos I established the "Royal and Pontifical University of Mexico" known today as the University of Mexico or la Universidad Nacional Autonimo de México (UNAM). Source: "The Oldest University in America" by C. E. Castañedain Hispania 1930 published by the American Association of Teachers of Spanish and Portuguese.
The oldest university in the western hemisphere is located in the Dominican Republic and is called Universidad Autónoma de Santo Domingo (UASD). It was founded in 1538, making it the oldest university in the Americas.
Alpha Kappa Alpha sorority was founded on Howard University Campus in 1908 which makes it the oldest sorority in America. It is also a African American founded Greek Letter Foundation.
The University was founded in 1842.
The first non-religious college in America was the University of Pennsylvania, founded in 1740 by Benjamin Franklin. It was established with secular principles and emphasized practical education and intellectual freedom.
Harvard, Yale, University of Pennsylvania, Princeton, and Kings College.
Harvard College, 1636 - founded on an endowment from John Harvard, an alumnus of Emmanuel College, Cambridge University, England.
California Baptist University was founded in 1950.