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Sex-linked genes
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∙ 13y ago
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How does hemophilia progress?
Hemophilia is a recessive allele condition. Men can get hemophilia alot easier than women as the allele is found on the XY Chomosome pair. With men. they do not have the extra "tail" on the Y chromosome compared to the XX with a female. If the person has the recessive allele on the X chromosome and this person is male, they will be a hemophiliac as they do not have a 'pair' allele which could be dominant to stop the condition expressing itself. On a female, if there is a recessive (hemophilia) allele on one of the X chromosomes but on the other is a Dominant (normal) allele then she will be a carrier of the faulty gene but will not suffer from the condition herself. If the female have a recessive (faulty) gene on each of the XX chromosomes, then she will be a sufferer of the disease.
Why is hemophilia more common in males than women?
this disease is caused by a recessive allele that is found only on the x chromosome. a human female has two x chromosomes. a human male only has 1 x chromosome. therefore, a male needs only one recessives allele to have hemophilia, while a female needs two recessive allele. as a result, hemophilia is much more common in males.
How many alleles for hemophilia do females have?
females have 2 alleles for hemophilia, (X^hX^H) and (X^hX^h) if H is the normal allele and h is the recessive allele for hemophilia
Is hemophilia caused by a dominant allele on the x chromosome true or false?
false
What chromosomes does hemophilia occur on?
Hemophilia is a X linked recessive disorder. Usually the mother is an unaffected carrier and her son unfortunately receives the X chromosome in which hemophilia is linked to.
Why is hemophilia more common in males than in females?
The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.
What chromosomes has been determined to carry this gene in hemophilia?
the X chromosome
Hemophilia is a sex linked recessive disorder Mary does not have the disease but both of her brothers do Neither of her parents have the disease What are Marys parents genotypes indicates pr?
Mary's father is normal and has a normal genotype XY while her mother is the carrier of hemophilia and has one X of her genotype infected i.e. she is X*X.
Which chromosome contains the gene for hemophilia?
The X chromosome. That's why it's more common in males; females have 2 X chromosomes, but males only have 1. So if a woman has the hemophilia mutation on one of her chromosomes, she probably won't be affected by it.
Hemophilia is a sex-linked recessive disorder. Mary does not have the disease, but both of her brothers do. Neither of her parents have the disease. What are Mary's parent's genotypes (* indicates presence of the hemophilia allele)?
X*X and XY
Why are men most likely to have hemophilia?
Since Hemophilia A is an "X Chromosome" disease and women have two "X" Chromosomes, women with only one "X" Chromosome with the disorder would be carriers of the disease but not affected by it. Women with both "X" Chromosomes with the disorder would be very rare.
Will a heterozygous female with hemophilia have blood that will clot normally?
Yes, because Hemophilia is recessive (if you have a normal allele, you won't have hemophilia, and heterozygous means that you have one normal and one abnormal allele).
