ther are different types of pathogens like bacteria and viruses which cause disease by self replicating.if we talk about bacteria it divide into two with in specific time i.e e.coli divide into 2 after every 20 minutes by replication.it divide its genome into 2 and synthesize new strands according to the semi conservative model.
Subtractive genomic strategy is developed by assuming that the novel targets identified in the pathogen should be essential for the pathogen that is it should be involved in the replication, survival and a important component of various metabolic pathways and mechanisms occurring in the pathogen while at the same time should be absent on the host that is human and should have no homologue in human, so that when a drug or a lead compound is designed considering the potential target it should only be against the mechanism and functionality of the pathogen not the host.
Viruses require host cells, whereas cells provide their own replication mechanisms.
DNA replication is significant in the reproduction of cells through the mechanisms of mitosis and meiosis. The DNA replicates so that there will be an extra DNA when the cell multiplies, allowing the "daughters" the chance to reproduce. DNA replication is significant in the reproduction of cells through the mechanisms of mitosis and meiosis. The DNA replicates so that there will be an extra DNA when the cell multiplies, allowing the "daughters" the chance to reproduce.
The fidelity of replication is backed by corrective mechanisms to ensure that said replication is a perfect as possible and the same protein structure is being coded for in the daughter cells. Naturally, no process is perfect and mutations will happen, but they are, generally, neutral.
An 'avirulent' pathogen is a pathogen which is not virulent.This is similar to 'atypical' which means 'not typical'
Subtractive genomic strategy is developed by assuming that the novel targets identified in the pathogen should be essential for the pathogen that is it should be involved in the replication, survival and a important component of various metabolic pathways and mechanisms occurring in the pathogen while at the same time should be absent on the host that is human and should have no homologue in human, so that when a drug or a lead compound is designed considering the potential target it should only be against the mechanism and functionality of the pathogen not the host.
Gaben at valve
As you probably know, colonization and infection are 2 separate events.Colonization occurs when a pathogen enters a wound then replicates.Once you have colonization/replication of a pathogen in a wound, the wound will (most likely) become infected.
Viruses require host cells, whereas cells provide their own replication mechanisms.
Non specific defense mechanisms are more effective because they work against all bacteria and viruses. Examples are skin or tears. Specific defense mechanisms like antibodies work against one type of bacteria or virus. They're needed if a pathogen gets past the nonspecific defense mechanisms.
DNA replication is significant in the reproduction of cells through the mechanisms of mitosis and meiosis. The DNA replicates so that there will be an extra DNA when the cell multiplies, allowing the "daughters" the chance to reproduce. DNA replication is significant in the reproduction of cells through the mechanisms of mitosis and meiosis. The DNA replicates so that there will be an extra DNA when the cell multiplies, allowing the "daughters" the chance to reproduce.
The fidelity of replication is backed by corrective mechanisms to ensure that said replication is a perfect as possible and the same protein structure is being coded for in the daughter cells. Naturally, no process is perfect and mutations will happen, but they are, generally, neutral.
Replication.
An 'avirulent' pathogen is a pathogen which is not virulent.This is similar to 'atypical' which means 'not typical'
The only way viruses can replicate is by parasitizing living cells and using the cell's mechanisms to replicate their genetic materials and protein components.
Every pathogen produces its own proteins and wastes (created during replication). Both of these can irritate the cells of a host (example: human being). The pathogen's proteins and wastes can cause nausea, vomiting, pus at wound sites, etc. Once the pathogen is stopped, such as with an antibiotic for bacterial pathogens, the "bug" no longer produces the proteins and its waste, so some symptoms begin to decrease as soon as the correct medication is introduced.
Replication Forks & Replication Bubbles