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It is 2-propylvaleric acid (or: 2-propyl-pentanoic acid),

structural formula (C3H7)2-CH-C(=0)(-OH), trivially known as 'dipropyl acetic acid'.

Valproic acid was first synthesized in 1882 by Burton as an analogue of valeric acid, found naturally in valerian.

The French researcher Pierre Eymard in 1962 serendipitously discovered the anticonvulsant properties of valproic acid.

Nowadays valproate is also known as folate antagonist with teratogenic properties for which women, wanting to become pregnant, should be warned when using it as an anticonvulsant and mood-stabilizing drug (primarily in the treatment of epilepsy, Bipolar disorder, and less commonly major depression).

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16y ago

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