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Active or inactive. The drug is changed by interaction with the body's own chemicals,enzymes and/or metabolic pathways.
The body for instance can bio-transform many substances into less toxic ones or some into more toxic ones. Let's take alcohol for instance...it is bio-transformed in the liver...in lower doses it will transform at a basic rate into a less toxic substance..if the enzymes in the liver are over whelmed by more alcohol than it can handle (it can't bio transform fast enough) then you get sick, or even go into a coma...

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Q: WHen drugs are biotransformed they become more?
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