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Q: Watson and Crick knew that the triple helix model of DNA that Linus Pauling had proposed was incorrect What evidence did they have for such a conclusion?
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Which scientist added an extra strand to the structure of DNA and won two Nobel Prizes?

Linus Pauling


How did Roselin Franklin contribute to the discovery of DNA?

She and Maurice Wilkins worked together and took some x-rays of DNA. The DNA crystallography allowed Watson and Crick to look at the picture to determine it was a double helix and not a triple helix as Linus Pauling had thought.


Did Watson and Crick steal Rosalind Franklin's discovery?

She and Maurice Wilkins worked together and took some x-rays of DNA. The DNA crystallography allowed Watson and Crick to look at the picture to determine it was a double helix and not a triple helix as Linus Pauling had thought.


Deficiency of vitamin C may result in?

Vit D is found in eggs and sunlight. A deficiency results in rickets in children and osteomalacia in adults. A deficiency prevents you from synthesising sufficient hydroxy appatite, the mineral component which hardens the collagen aspect of bones, making them weak and bendy.


How did Watson and crick determine the three demensional shape of DNA?

When Francis Crick began his research, it was still unknown WHERE and HOW genetic codes for life were kept. In other words, nobody knew how a fertilized human egg "knew" to grow into a human while a fertilized rose seed "knew" to grow into a rose -- the location of this genetic information in terrestrial life was speculative at best. Some thought it was in the proteins within cells, others thought it might be in a cell's DNA -- a chemical found in all living cells, but for which nobody knew its function. Linus Pauling of Caltech (along with other co-workers) analyzed x-ray diffraction patterns of proteins, and was able to surmise that each had a helical structure. He was thus on his way to discover the structure of DNA, and might have done so first except (1) he lacked high quality x-ray patterns and (2) he began with a mistaken idea that it was a triple helix. Both he and Francis Crick surmised that any genetic code needed to be stable over many years, and thus the structure of this code had to involve very strong chemical bonds. They also both knew that DNA consisted of four amino acids, and that two of these were always found to be equal in volume to two others. The question then became HOW these amino acids combined. When Crick and Watson observed the high quality "Photo 51," they observed a helical pattern for DNA, and were even able to make a rough estimate of its size. This was despite the fact that Dr. Franklin vehemently disagreed with their analysis. The two of them made a model of DNA based on their hunches, but this model turned out to be embarassingly wrong -- something Franklin was able to note in a matter of minutes. They had placed molecules on the outside of DNA that, if the molecules had come in contact with water, the DNA structure would have collapsed. Changing the basic structure so that these molecules were on the inside, C & W were able to make a model that fit all the requirements noted above. A few months later they speculated that the genetic code for all Earth life was "recorded" in the structure of DNA. Within a few years, they were shown to be correct.

Related questions

What was the first DNA model called?

The first correct shape was the double helix by Watson and Crick. However, there were earlier incorrect models, for example the incorrect triple helix model proposed by Linus Pauling. Even the first model by Watson and Crick turned out to be incorrect; they had it inside out compared to the correct model.


What is the birth name of Linus Pauling?

Linus Pauling's birth name is Linus Carl Pauling.


What is the electronegativity of O?

The Pauling electronegativity of O is 3,44.


What is the electroneutrality principle?

Proposed by Linus Pauling (1901-1994), states that the atoms in a molecule share electrons in a manner which makes the charge on each atom as close to zero as possible.


How tall is Alexis Pauling?

Alexis Pauling is 5' 8".


How tall is Bernadette Pauling?

Bernadette Pauling is 5' 4".


What nicknames does Alexis Pauling go by?

Alexis Pauling goes by Aehlex.


What is linus pauling?

Linus Pauling was born on February 28, 1901.


What actors and actresses appeared in Interview with Linus Pauling - 1960?

The cast of Interview with Linus Pauling - 1960 includes: Linus Pauling as himself


When did Linus Carl Pauling die?

Linus carl pauling died in 1994


When was Linus Pauling born?

Linus Pauling was born on February 28, 1901.


What is Linus Pauling's birthday?

Linus Pauling was born on February 28, 1901.