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What else can I help you with?
Which has a higher Vmax: glucokinase or hexokinase?
Glucokinase
Why is glucokinase inactive in the nucleus?
Glucokinase Regulatory Protein is found in the nucleus which binds glucokinase to inactive it
What are glucokinase deficiency?
Glucokinase deficiency is a rare genetic disorder that affects the enzyme glucokinase, which plays a crucial role in glucose metabolism by facilitating the conversion of glucose to glucose-6-phosphate in the liver and pancreas. This deficiency leads to impaired insulin secretion and results in a form of diabetes known as maturity-onset diabetes of the young (MODY). Patients may experience episodes of hyperglycemia and hypoglycemia, particularly during fasting or illness, due to the enzyme's inability to effectively regulate blood sugar levels. Management typically involves dietary modifications and monitoring blood glucose levels.
where is glucokinase active intracellularly?
in the cytosol
What is the glucose sensor in B-cells Why?
glucokinase. glucokinase has a high km(low affinity for glucose) so glucokinase only phosphorylates glucose when blood glucose is high, such as after a meal. As such, it makes sense that this would be sensor for B-cells
What happens if you are lack of vitamins?
Vitamin deficiency
What enzyme catalyze the phosphorylation of glucose after a meal?
glucokinase
What enzyme phosphorylates 90% of the glucose in the liver?
glucokinase
Which has a higher affinity for glucose: hexokinase or glucokinase?
Hexokinase
What happens if vitamin k deficiency occurs?
kwashiorkore
Which of the following is characteristic of hexokinase (as opposed to glucokinase)?
It is not inducible by insulin
Where is glucokinase located intracellularly?
equilibriates between the nucleus and cytosol
