You can't produce insulin
Glucokinase
Glucokinase Regulatory Protein is found in the nucleus which binds glucokinase to inactive it
in the cytosol
glucokinase. glucokinase has a high km(low affinity for glucose) so glucokinase only phosphorylates glucose when blood glucose is high, such as after a meal. As such, it makes sense that this would be sensor for B-cells
Vitamin deficiency
glucokinase
glucokinase
Hexokinase
kwashiorkore
It is not inducible by insulin
equilibriates between the nucleus and cytosol
You could get a disease called rickets if you have a Vitamin D deficiency.