Glucokinase Regulatory Protein is found in the nucleus which binds glucokinase to inactive it
equilibriates between the nucleus and cytosol
Glucokinase
in the cytosol
glucokinase. glucokinase has a high km(low affinity for glucose) so glucokinase only phosphorylates glucose when blood glucose is high, such as after a meal. As such, it makes sense that this would be sensor for B-cells
glucokinase
glucokinase
Hexokinase
You can't produce insulin
It is not inducible by insulin
Pancreatic Beta cells and liver hepatocytes. Read more in link.
Glucokinase is often referred to as the 'glucose sensor' as it directly relates the rate of β-cell glucose-dependent insulin secretion and the rate of hepatocyte glucose metabolism to the ambient blood glucose level. Read more in related link below.
It specifically phosphorylates glucose, rather than other sugars.