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What else can I help you with?
Where is glucokinase located intracellularly?
equilibriates between the nucleus and cytosol
Which has a higher Vmax: glucokinase or hexokinase?
Glucokinase
Why is glucokinase inactive in the nucleus?
Glucokinase Regulatory Protein is found in the nucleus which binds glucokinase to inactive it
where is glucokinase active intracellularly?
in the cytosol
What is the glucose sensor in B-cells Why?
glucokinase. glucokinase has a high km(low affinity for glucose) so glucokinase only phosphorylates glucose when blood glucose is high, such as after a meal. As such, it makes sense that this would be sensor for B-cells
What enzyme catalyze the phosphorylation of glucose after a meal?
glucokinase
What enzyme phosphorylates 90% of the glucose in the liver?
glucokinase
Which has a higher affinity for glucose: hexokinase or glucokinase?
Hexokinase
What happens if you have a glucokinase deficiency?
You can't produce insulin
Which of the following is characteristic of hexokinase (as opposed to glucokinase)?
It is not inducible by insulin
How is glucokinase regulated?
Glucokinase is often referred to as the 'glucose sensor' as it directly relates the rate of β-cell glucose-dependent insulin secretion and the rate of hepatocyte glucose metabolism to the ambient blood glucose level. Read more in related link below.
Which one of these applies to the enzyme glucokinase?
It specifically phosphorylates glucose, rather than other sugars.
