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The only Opiate that I know of with a ceiling effect is Suboxone which is 32mg(probably because it has Naloxone in it but I'm not sure if that's why). But that is a VERY high dose for a non-tolerant user. This ceiling effect can also be broken if taken with Benzodiazepines, Alcohol, and probably Barbiturates too. Other Opiates like Oxycodone don't have a ceiling effect and can be deadly to those who are not tolerant to it's effects. Also don't take other people's advice on how much to take (besides a doctor or pharmacist.) That goes for any Opiate. One man's dose could be another man's death sentence (or woman's of course.) Always look up pills with a well respected Pill ID source (I use Drugs.com). And always look up or ask a doc or pharmacist what a normal starting dose is. Opiates are very addictive as well so it's best to only use them if you DON'T have a source of getting a bunch more. But it's best to stay away from them completely if you can. Ignorance is bliss with taking those things and every opiate addict who isn't take them for physical pain as prescribed know what I'm talking about. I say if you have to try drugs and be a "rebel." Stick to a little weed. And if you say "Weed is getting boring. I wanna try something stronger." You should re-evaluate you current life situation and quit using drugs all together. And no this isn't a drug councilor talking, it's a 21 year old recovering drug addict. I've been there from cigarettes to weed to heroin and others in between and believe me you will always think it won't happen to you but why take the chance. Why "experiment" with something you will either love and want to do again or not like and wish you hadn't done it. It's not worth it. ......so anyway there is no ceiling effect on Opiates except Suboxone which is 32mg. .....I got a little off topic didn't I. But it's just because once your a drug addict, you can't un-become one. It's something you will have to deal with the rest of your life even if you stop using. I wouldn't wish it on my worst enemy and Opiates are probably the easiest drug to get addicted to because of how good they make you feel. And if your reading this picturing that I'm some getto hood rat, I'm not. I'm a white Christian conservative from the Southern California suburbs. So it can happen to anyone. Just warning you. Ignorance is bliss. The nalaxone has no effect on the ceiling effect of the chemical called buprenorphine, I am a user of subutex generic is called buprenorphine it in itself has a cieling effect, in fact I get a ceiling effect at 8 milligrams, if I take more than 8 mills it does nothing more to me, I can take 24 mills or 32 mills or I can take 100 mills it makes no difference, taking more than 8 mills does nothing more to me, this is why doctors have been allowed to prescribe this to addicts, it is not an abusable drug. Yes one can inject pure buprenorphine and I have done this, it is not worth the trouble. The nalaxone in soboxone is there to prevent one from injecting it, nalaxone has a large molocule and is not absorbed in ones mouth is only works if one injects it.

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Q: What Is the ceiling affect pertaining to opiates?
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