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Ibuprofen brand name: Advil, Children's Advil / Motrin, Medipren, Nuprin, Pediacare Fever etc.

ibuprofen belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). These drugs are used for the management of mild to moderate pain, fever, and inflammation. Prostaglandins are chemicals that are made by the body and are responsible for causing pain, fever and inflammation. Ibuprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower levels of prostaglandins. As a consequence, inflammation, pain and fever are reduced.

Ibuprofen Drug Interactions

Ibuprofen is associated with several suspected or probable interactions that can affect the action of other drugs. Ibuprofen may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When ibuprofen is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to aminoglycoside-related side effects. Individuals taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid ibuprofen because ibuprofen also thins the blood, and excessive blood thinning may lead to bleeding.

Ibuprofen Side Effects

The most common ibuprofen side effects are rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation and heartburn. Serious Ibuprofen side effect is ulceration of the stomach or intestine, and the ulcers may bleed. Sometimes, ulceration and bleeding can occur without abdominal pain, and black tarry stools, weakness, and dizziness upon standing (orthostatic hypotension) may be the only signs of a problem. Renal ibuprofen side effects include reduction of blood flow to the kidneys and impaired function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of ibuprofen in these patients should be done cautiously. People who are allergic to other NSAIDs, including aspirin, should not use ibuprofen. Individuals with Asthma are more likely to experience allergic reactions to ibuprofen and other NSAIDs.

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12y ago
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14y ago

Paracetamol, also known as acetaminophen or APAP, has two beneficial effects on your body. (1) It reduces fever (2) It relieves mild pain. However, it also presents a risk to your body. Even a small overdose of this medication can cause serious and even fatal damage to your liver. APAP overdose is one of the most frequent causes of poisoning, according to the US National Institutes of Health and other health organizations. One of the problems is that APAP is used as an ingredient in so many prescribed and over-the-counter compounds (ingredient combination products), and people often don't pay attention to ingredients. Someone who has a really uncomfortable respiratory infection takes a cold therapy medicine, a flu therapy medicine, and then an extra-strength Tylenol or Panadol tablet for their headache; oops, they've just taken a triple-dose of APAP.

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Q: What affects does paracetamol have on your body?
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Does paracetamol affect the brain?

Paracetamol affects the brain by slowing down and stopping pain signals travelling across the Synapse, tricking the body into believing the pain has gone.


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Paracetamol affects the root elongation in certain plants such as wheat, as well as the wheat shoot itself. Paracetamol significantly decreased both parameters, and after a while the paracetamol damages the chlorophyll accumulation and the protein synthesis of the plant.


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Can you take paracetamol and Ibuprofen together for sciatica?

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Why is paracetamol used?

Paracetamol is used to reduce temperature in body which we call Antipyritic. it is also the to reduce pain which we call Antagic as well.


How does paracetamol reduce temperature?

Paracetamol reduces body temp by acting on the area of the brain which is responsible for temp control. (See Hypothalamus)


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