Drugs that block catechol-o-methyl transferase, an enzyme that breaks down dopamine
COMT inhibitors include entacapone and tolcapone
Catechol-O-methyltransferase (COMT) inhibitors are a class of medication used in combination with levodopa and carbidopa in the treatment of symptoms of Parkinson's disease (PD).
COMT is a medical designation issued by JCAHPO or the Joint Commission on Allied Health Personnel in Ophthalmology. COMT is Certified Ophthalmic Medical Technologist. A COMT would work directly under an ophthalmologist and be responsible for whatever tasks he/she is assigned.
Certified Orthopedic Manual Therapist
There are two classes of the drugs: dopaminergics and anticholinergics. The dopaminergic drugs include the following: A: Levodopa drugs: such as levodopa and madopar B: Dopamine releasing agents (DRAs), such as amantadine and memantine C: Dopamine agonists, such as piribedil and pramipexoleD: MAO-B inhibitors,such as selegiline E: Catechol-O-methyl transferase(COMT) inhibitors: such as entacapone and tolcapone Anticholinergics include trihexyphenidyl, benztropine mesylate etc.
to germinate inhibitors
Norepinephrine is primarily broken down by the enzyme monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) in the liver and other tissues. MAO oxidizes norepinephrine into its metabolite, dihydroxyphenylglycol (DHPG), while COMT methylates norepinephrine into normetanephrine.
Monoamine oxidase inhibitors
Competitive inhibitors compete with the substrate for the enzyme's active site, while noncompetitive inhibitors bind to a different site on the enzyme. Competitive inhibitors can be overcome by increasing substrate concentration, while noncompetitive inhibitors cannot. Both types of inhibitors reduce enzyme activity, but competitive inhibitors specifically affect the binding of the substrate, while noncompetitive inhibitors can alter the enzyme's shape or function.
Comt cheese pairs well with fruits like apples, pears, and grapes, as well as nuts like walnuts and almonds. It also goes well with cured meats like prosciutto and salami, as well as crusty bread and a glass of white wine.
They are also called DC inhibitors
They are also called DC inhibitors