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Any drug that is in the narcotic family, especially muscle relaxants. You need a doctor's prescrption to obtain any of these types of drugs. The muscle would not actually weaken, only become more relaxed as a result of the drug's effects.

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14y ago
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12y ago

Drugs that increase the lower esophageal sphincter tone are anti cholinergics such as( atropine,hyoscine,pyrollate,) ca channel blockers (verapamil,nifedepine) and NSAIDs and few of the antibiotics.

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Q: What drugs reduce lower esophageal sphincter tone?
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