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When two or more hormones work together to produce a particular result, their effects are said to be synergistic. These effects may be additive or complementary. The action of epinephrine and norepinephrine on the heart is a good example of an additive effect. Each of these hormones separately produces an increase in cardiac rate; acting together in the same concentrations, they stimulate an even greater increase in cardiac rate.

The synergistic action of FSH and testosterone is an example of a complementary effect; each hormone separately stimulates a different stage of spermatogenesis during puberty, so that both hormones together are needed at that time to complete sperm development.

Likewise, the ability of mammary glands to produce and secrete milk requires the synergistic action of many hormones-estrogen, cortisol, prolactin, oxytocin, and others.

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Q: What are examples of synergisteric hormones?
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