Yes it can do, the body produces histomines in an allergic reaction such as hayfever or pet hair allergies, so we take anti-histamines to counteract the symptoms.
The cells involved in inflammation are the cells that release cytokines which include: interferons, tumor necrosis factor, interleukins, and chemokines. All of which can result in inflammation since they increase vascular diameter leading to an increase in blood flow and they also attract phagocytic cells that release inflammatory mediators causing pain. These cells include macrophages, neutrophils,and eosinophils.