they are important in the nervous system
they lead to chnages in sodium and calcium concentrations in cells
they open or close in response to a chemical signal
Ionotropic receptors are ligand-gated or transmitter gated ion channels. The binding of a neurotransmitter or other ligand to a particular site on a domain of a protein in the receptor causes a conformational change in the protein subunits. This allows a certain ion to pass through, poteitally potassium, sodium or chloride. There are two types of ionotropic receptors, non-NMDA and NMDA. Both are ligand gated receptors, however the NMDA is also voltage gated.
An action potential is propagated in a neuron through the activation of various voltage-gated and ligand-gated ion channels. Examples include sodium and calcium channels and nicotinic-acetylcholine receptors.
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
A specific molecule binding to it
It is a carrier protein
There are voltage-gated ion channels and ligand-gated ion channels, and since both are stimuli the term stimulus-gated is a redundancy.
It is a channel through a membrane that can be opened or closed by chemical or electrical events.
Ionotropic receptors are ligand-gated or transmitter gated ion channels. The binding of a neurotransmitter or other ligand to a particular site on a domain of a protein in the receptor causes a conformational change in the protein subunits. This allows a certain ion to pass through, poteitally potassium, sodium or chloride. There are two types of ionotropic receptors, non-NMDA and NMDA. Both are ligand gated receptors, however the NMDA is also voltage gated.
An action potential is propagated in a neuron through the activation of various voltage-gated and ligand-gated ion channels. Examples include sodium and calcium channels and nicotinic-acetylcholine receptors.
When acetylcholine binds to receptors at the motor plate, this binding opens ligand-gated ion channels on the motor end plate, ions diffuse through the open ligand gated ion channels, and the flow of ions causes the motor end plate to reach threshold and an action potential is generated at the motor end plate.
Agonists tend to work in favor of something, therefore an agonist for a ligand-gated ion channel would open the channel whereas an antagonist would prevent it from opening.
Membrane receptors at a synapse are ligand-gated ion channels that open and allow sodium ions to flow into the neuron upon binding of the neurotransmitter ligand to generate an action potential in the neuron.
A specific molecule binding to it
voltage-gated ion channels
It is a carrier protein
G protein-gated ion channels are specific ion channels located in the plasma membrane.
gated