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Monospecific Polyclonal antibodies are produced by not just a common germ cell like monoclonal antibodies, but from other products. Monospecific antibodies have affinity for the same antigen.
Wiki User
∙ 9y ago
Wiki User
∙ 10y agoMonoclonal means that they are cloned from a unique, single immune cell. This makes them identical cells that will make a single antibody that will cling to the cells of a specific disease.
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What is a sentence that has polyclonal in it?
Polyclonal antibodies showed up in the blood test.Rabbits are the most common animal for polyclonal antibody production.Chickens are sometimes used for polyclonal antibody production.
What is the advantage of using monoclonal antibodies?
A single clone, ie a bunch of identical antibodies. As opposed to polyclonal antibodies, which are different clones even though they bind the same antigen.
Construction and fermentation of Antibody drug?
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope. Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see "Nomenclature of monoclonal antibodies"), and many immunotherapy specialists use the word mab anacronymically.
Why polyclonal antibody tend to have cross-reaction compare to monoclonal antibody?
Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope, hence monoclonal antibodies are more specific than polyclonal antibodies. However, sometimes MAbs are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since some of the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein this is the reason for the tendency of polyclonal antibodies to have cross-reaction as compared to MAbs. by Victor S Gruezo Jr
What is a genus with single species?
A genus with one species is a monospecific genus.
What has the author Hong Li written?
Hong Li has written: 'Analysis of bovine herpesvirus 4 (DN 599) proteins with monoclonal antibodies and polyclonal immune serum' -- subject(s): Viruses, Herpesvirus diseases in animals, Cattle
What is the different between polyclonal antibody and antiserum?
polyclonal antobody is the antibody produced for many or non specific antigens but antiserum is the antibody for a specific antigen
Why polyclonal antibody solution is able to precipitate its antigen protein whereas monlclonal antibody solution has hard time to do so?
Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope. Sometimes, monoclonal antibodies are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein.
Multiple antibody binding to single antigen?
Polyclonal antibody
What does testing the lymphoproliferative response of mononuclear cells to polyclonal stimulators mean?
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Difference between monoclonal antibody and polyclonal antibody?
Polyclonal antibodiesMonoclonal antibodiesInexpensive to produceExpensive to produceTechnology required is lowHigh technology requiredSkills required are lowTraining is required for the technology useTime scale is shortTime scale is long for hybridomasProduces large amounts of non specific antibodiesCan produce large amounts of specific antibodies but may be too specificRecognizes multiple epitopes on any one antigenRecognizes only one epitope on an antigenCan be batch to batch variabilityOnce a hybridoma is made it is a constant and renewable source and all batches will be identical
What is the medication for polyclonal increase in gamma globulin consistent with infection linflammation?
so far my knowledge is concerned no medicatin is needed.
