Their standard of living; their geographical location; their access to health care and maybe history of that disease in the family.
Susceptibility to STDs involves many factors including the individual's own immune response which helps to determine whether infection occurs. A very invasive STD infection is considered PID.
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Recent advances in gene mapping have led to the discovery of genetic factors that increase a child's susceptibility to otitis media.
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It is also possible that genetic factors are involved in susceptibility to leprosy.
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