The basic cause is too many people.
yes it cause major destruction
Guns do not cause destruction. They may be used by people that cause destruction.
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loss of habitat
Yes. Tornadoes are well known for the death and destruction they cause.
Bengal Tigers are not in fact extinct, though three sub species are. The cause of the extinction of these three sub species are over hunting, and habitat destruction. The same goes for the Endangering of the other six sub species still alive today. http://en.wikipedia.org/wiki/Tigers
because different species could mate and make new species which could cause diseases and disabilities in new species.
cause
CFC's are main cause of destruction of ozone layer. They react with ozone to deplete it.
hunting and habitat destruction
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exctintion