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Their R groups. Some are basic, some are acidic, some are hydrophobic, some are hydrophillic and some are polar. These groups, all extending from the same amino acid base, interact in many different ways with each other chemically and twist and fold the polypeptide structure into a mature protein. Form dictates function in these proteins.

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Q: What are the major properties that distinguish different amino acids from one another. What roles do these differences play in the structure and function of proteins?
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