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What is mechanism of action of ribavirin?
Ribavirin’s mechanism of action is not fully understood, but it is believed to inhibit the replication of RNA and DNA viruses by interfering with their genetic material. It may disrupt viral RNA synthesis and impair viral mRNA capping. Ribavirin has also been shown to have immunomodulatory effects, such as enhancing the activity of natural killer cells.
What is the toxicity of ribavirin?
In rare cases, initiation of ribavirin therapy has led to deterioration of respiratory function in infants.
What is ribavirin?
Ribavirin is an anti-viral drug indicated for severe RSV (Human respiratory syncytial virus) infection, hepatitis C infection and other viral infections. Ribavirin is a prodrug, which when metabolised resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for viral replication.
What is effective against respiratory syncytial virus?
Ribavirin (Virazole) is used to treat respiratory syncytial virus. In combination with interferons, ribavirin has shown some efficacy against hepatitis C
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