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malaria is a serious infectious disease indigenous to tropical and subtropical areas, particularly sub-Sahara Africa, where 90% of malaria-related deaths occur. The primary mode of transmission is via the bite of an infective female Anopheles' mosquito, which is the only species capable of transmitting malaria (protozoan) parasites.

The mosquito, itself, does not have malaria, but carries the parasite from one infected person to another by incubating the microorganisms in donor blood. About a week later, during her next feeding cycle, she injects the microscopic pathogens into a new host through a mixture of tainted blood and saliva. Once inside the human body, malaria parasites multiply within the red blood cells.

There are five distinct species of the malaria (plasmodium) parasite that can infect humans. The most serious form of the disease is caused by Plasmodium falciparum, which results in 1-3 million deaths per year, primarily in young children. The total annual infection rate is 350-500 million cases, making malaria one of the most serious public health problems in Africa.

Symptoms of malaria include anemia, light-headedness, shortness of breath, tachycardia (fast heart rate), fever, chills, nausea, and muscle aches. More severe infections may be accompanied by retinal damage, renal failure, brain swelling, seizures, coma and death. For those who survive, malaria may become chronic, lapsing and remitting over time and requiring intermittent hospitalization and ongoing treatment with anti-malarial drugs like chloroquine, quinine, and amodiaquine. Unfortunately, the dangerous Plasmodium strain is developing treatment resistance to some of these drugs.

At present, there is no vaccine for malaria, although there are several in development. Preventative measures are currently directed at mosquito control.

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Q: What are the three ways to transmit malaria?
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What are 5 ways to prevent malaria?

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