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What are thunderclappers?

Updated: 9/24/2023
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Q: What are thunderclappers?
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Did Lewis and Clark bring their medicine or did the Native Americans give them it?

After consulting with Dr. Benjamin Rush of Philadelphia, a leading physician of the day, one of the chief medicines were purgative or cleansing tablets known as Dr. Rush's patented pills or "Thunderclappers." The Voyage of Discovery took along 600 of these tablets. Stephen Ambrose wrote in his book "Undaunted Courage: Meriwether Lewis, Thomas Jefferson and the Opening of the West" that "Dr. Rush thought these pills would cure any number of ills." They were made with calomel (six parts mercury to one part chlorine) and jalap (think jalapeno pepper, used as a purgative). The medical supplies, bought in St. Louis, totaled $90.69. They included: lancets, forceps, tourniquets, clysters (enema) syringes, gonorrhea syringes, Peruvian bark (quinine), calomel, jalap, laudanum/opium, Glauber salts (sodium sulfide, a mild laxative), niter (potassium nitrate/saltpeter, a diuretic), tartar emetic (produces vomiting) and mercurial ointment (mercury/fat to soothe irritations). The list suggests gastro-intestinal complaints were common and expected. The poor flow of bile was believed to cause many infirmities, including constipation and headaches. Dr. Rush's tablets were anti-bilous tablets. In addition to pains from the hard labor, the explorers suffered wounds from gunshot, snakebite, scalded feet, dysentery, and other injuries and ailments. Besides internal treatment, they used saltpeter for wounds, using bark to make a poultice. Dr. Rush's advice was often prevantative in scope, advising to wash their feet with cold water, to purge the body, to wear flannel next to the skin and other theories. While the medicines and techniques may sound primitive by today's standards (not to mention ignorant about concerns of mercury poisoning), only one man died on the journey.